Sponges from Ceylon

Pneumoconiosis in a Coalworker from Ceylon.

This report includes the clinical, radiological, morbid anatomical, and histological findings in the lungs of a man who for a continuous period of 45 years had been engaged in the loading and unloading of coal in ships and trains. He presented as a case of congestive cardiac failure with signs of severe pulmonary hypertension. The chief feature in the lungs was the presence of silicoticlike nod...

Kinase Inhibitors from Marine Sponges

Protein kinases play a critical role in cell regulation and their deregulation is a contributing factor in an increasing list of diseases including cancer. Marine sponges have yielded over 70 novel compounds to date that exhibit significant inhibitory activity towards a range of protein kinases. These compounds, which belong to diverse structural classes, are reviewed herein, and ordered based ...

Producing drugs from marine sponges.

Marine sponges are potential sources of many unique metabolites, including cytotoxic and anticancer compounds. Natural sponge populations are insufficient or inaccessible for producing commercial quantities of metabolites of interest. This review focuses on methods of producing sponge biomass to overcome supply limitations. Production techniques discussed include aquaculture in the sea, the con...

Prehistoric Archreology in Ceylon

The Ceylon Medical School

session, and we learn from a report submitted by the Principal Dr. James Loos that six students out of eleven who presented themselves, after having undergone a searching examination, have been found qualified to practise medicine and surgery, and have been recommended to the colonial government for a license. The subjects taught in this school are descriptive and surgical anatomy, general anat...